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Public Health Well

Ocuphire completes financing round for advancement of Nyxol

Ocuphire Pharma has closed $5 million in financing to support multiple phase 2 trials of Nyxol, its lead drug candidate, according to a press release. Nyxol, an ophthalmic solution eye drop containing phentolamine mesylate and designed to treat front-of-th ...

Crisaborole ointment possible first-line agent in psoriasis for thin, sensitive skin

In a pilot study, crisaborole ointment 2% led to significant lesion improvement in intertriginous, anogenital and facial psoriasis and may serve as a first-line therapy in these sensitive skin regions. “Treatment with this agent could allow for avoidance o ...

FDA approves first generic alternatives to Lyrica

The FDA has approved several generic versions of pregabalin for the treatment of patients with neuropathic pain related to diabetic neuropathy, postherpetic neuralgia, partial onset seizures, fibromyalgia and spinal cord injury. “Today’s approval of the fi ...

Open consultation: Advancing our health: prevention in the 2020s

We want your views on proposals to help people live healthier, happier lives for longer. ...

Higher levels of anti-NA antibodies may blunt severity of flu

Study findings showed that antibodies against the influenza surface protein neuraminidase are associated with a significantly shortened period of viral shedding in children and adults, and with shortened influenza symptom duration in adults, researchers re ...

Latarjet procedure, iliac crest bone graft transfer for shoulder instability yield similar outcomes

According to recently published results, there was no difference seen in clinical and radiologic outcomes with the Latarjet procedure and iliac crest bone graft transfer procedure. However, patients who underwent the Latarjet procedure had worse internal r ...

TMS can offer relief from anxiety

by Lindsay Israel, MD Transcranial magnetic stimulation, or TMS, is an FDA-approved, noninvasive treatment for major depression using magnetic pulses targeted at a specific location on the brain. TMS is a completely outpatient procedure and is gaining mome ...

Metabolic abnormalities persist for lean women with PCOS

The prevalence of obesity in a cohort of Italian women with polycystic ovary syndrome was much lower than that of similar women living in the United States; however, metabolic risks for these women persist despite having a lower BMI, according to findings ...

Contact Lens Start-Up, Big on Social Media, May Be Bad for Eyes, Doctors Say

The company, Hubble, offers customers contact lens subscriptions at low monthly prices. Critics say it bypasses eye care professionals, doesn’t properly vet prescriptions and takes advantage of federal regulations to the detriment of consumers. ...

Five Things to Know About Rabies

One of the world’s most studied and preventable diseases is still a deadly and common threat in much of the world. ...

NAFLD, NASH leading 'economic tsunami' of liver disease in US

Stephen A. Harrison, MD, FACP, FAASLD, visiting professor of hepatology at University of Oxford and medical director at Pinnacle Clinical Research, discussed how the growing epidemic of liver disease impacts the financial solvency of the U.S. health care s ...

Treating patients with migraine: What PCPs need to know

There is a 6-month waiting list for an appointment at Montefiore Headache Center, which Richard B. Lipton, MD, directs — with similar circumstances playing out at other clinics for migraine and headache care. With the lack of resources, the number of affec ...

Tsepamo: 3 in 1,000 infants exposed to dolutegravir have neural tube defects

According to results from the ongoing Tsepamo study in Botswana, infants born to women who took the integrase inhibitor dolutegravir for HIV infection from conception remained at an elevated risk for neural tube defects, with three in 1,000 born with these ...

The Downside of Having a Sweet Tooth

Regular consumption of sugary drinks heightens the risk not only of tooth decay, obesity, fatty liver disease and Type 2 diabetes, but also of heart disease and premature death. ...

FDA approves application to expand Doptelet for autoimmune bleeding disorder

FDA approved a supplemental new drug application to expand the use of Doptelet to include the treatment of thrombocytopenia in adults with chronic immune thrombocytopenia who had an insufficient response to a previous treatment, according to a press releas ...

Anti-TNF persistence lower among women with IBD

Higher rates of side effects lead to lower drug persistence of anti-TNF therapy among women with inflammatory bowel disease, according to study results. Herma H. Fidder, of the department of gastroenterology and hepatology at University Medical Centre Utre ...

Contact lens subscription programs foster patient loyalty

by Elise Kramer OD, FAAO, FSLS Specialty lenses are the main focus of my practice, and I believe every contact lens specialist should offer a wide variety of soft contact lenses to our many patients who have “normal eyes measured ocular surfaces,” or as my ...

Diabetes confers greater heart failure risk for women vs. men

Both type 1 and type 2 diabetes are stronger risk factors for developing heart failure for women vs. men, suggesting a sex-specific approach is needed in diabetes research and clinical practice, according to an analysis of more than 12 million adults publi ...

Plant-based diets effective for prevention of type 2 diabetes

Adherence to a plant-based dietary pattern reduced the risk for type 2 diabetes, suggesting it may play a role in primary prevention, according to a study published in JAMA Internal Medicine. “Plant-based dietary patterns, which emphasize foods derived fro ...

Elective surgery increases risk for worse outcomes in HF

Patients with HF who underwent elective ambulatory surgery had an increased risk for 30-day postoperative complications and 90-day mortality regardless of the presence of HF symptoms, according to a study published in JAMA Surgery. “These data may be helpf ...