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Health Well

Linkage of Maternity Hospital Episode Statistics data to birth registration and notification records for births in England 2005-2014: methods. A population-based birth cohort study

Introduction Maternity Hospital Episode Statistics (HES) data for 2005–2014 were linked to birth registration and birth notification data (previously known as NHS Numbers for Babies or NN4B) to bring together some key demographic and clinical data items no ...

Community-based rehabilitation training after stroke: results of a pilot randomised controlled trial (ReTrain) investigating acceptability and feasibility

Objectives To assess acceptability and feasibility of trial processes and the Rehabilitation Training (ReTrain) intervention including an assessment of intervention fidelity. Design A two-group, assessor-blinded, randomised controlled trial with parallel m ...

Adapting and enhancing PAX Good Behavior Game for First Nations communities: a mixed-methods study protocol developed with Swampy Cree Tribal Council communities in Manitoba

Introduction High rates of mental health problems, such as suicidal behaviours, among First Nations youth in Canada are a major public health concern. The Good Behavior Game (GBG) is a school-based intervention that provides a nurturing environment for chi ...

Cost-effectiveness of a community-delivered multicomponent intervention compared with enhanced standard care of obese adolescents: cost-utility analysis alongside a randomised controlled trial (the HELP trial)

Objective To undertake a cost-utility analysis of a motivational multicomponent lifestyle-modification intervention in a community setting (the Healthy Eating Lifestyle Programme (HELP)) compared with enhanced standard care. Design Cost-utility analysis al ...

Feasibility, acceptability and effectiveness of an online alternative to face-to-face consultation in general practice: a mixed-methods study of webGP in six Devon practices

Objectives To evaluate the feasibility, acceptability and effectiveness of webGP as piloted by six general practices. Methods Mixed-methods evaluation, including data extraction from practice databases, general practitioner (GP) completion of case reports, ...

Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey

Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals in northern, cent ...

Management of type 2 diabetes mellitus in people with severe mental illness: an online cross-sectional survey of healthcare professionals

Objectives To establish healthcare professionals’ (HCPs) views about clinical roles, and the barriers and enablers to delivery of diabetes care for people with severe mental illness (SMI). Design Cross-sectional, postal and online survey. Setting Trusts wi ...

GP and parent dissonance about the assessment and treatment of childhood eczema in primary care: a qualitative study

Objectives To compare parents’ and clinicians’ perspectives on the assessment and treatment of children with eczema in primary care. Design Qualitative interview study with purposive and snowball sampling and thematic analysis. Setting 14 general practices ...

Delivering safe and effective test-result communication, management and follow-up: a mixed-methods study protocol

Introduction The failure to follow-up pathology and medical imaging test results poses patient-safety risks which threaten the effectiveness, quality and safety of patient care. ...

Clinical validation of a public health policy-making platform for hearing loss (EVOTION): protocol for a big data study

Introduction The holistic management of hearing loss (HL) requires an understanding of factors that predict hearing aid (HA) use and benefit beyond the acoustics of listening environments. Although several predictors have been identified, no study has expl ...

Transcranial DC stimulation modifies functional connectivity of large-scale brain networks in abstinent methamphetamine users

Abstract Background Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool suited to alter cortical excitability and activity via the application of weak direct electrical currents. An increasing number of studies in the add ...

Impact of nonintrusive clinical decision support systems on laboratory test utilization in a large academic centre

Abstract Background The near-universal prevalence of electronic health records (EHRs) has made the utilization of clinical decision support systems (CDSS) an integral strategy for improving the value of laboratory ordering. Few studies have examined the ef ...

Individualized, supportive care key to positive childbirth experience, says WHO

WHO has issued new recommendations to establish global care standards for healthy pregnant women and reduce unnecessary medical interventions. Worldwide, an estimated 140 million births take place every year. Most of these occur without complications for w ...

Biogeographical distribution of bacterial communities in Changbai Mountain, Northeast China

Abstract The broad-leaved and Korean pine mixed forest in Changbai Mountain, China is an important component of boreal forest; the area is sensitive to global climate change. To understand spatial distribution patterns of soil bacterial community along ele ...

Improved protocols to accelerate the assembly of DNA barcode reference libraries for freshwater zooplankton

Abstract Currently, freshwater zooplankton sampling and identification methodologies have remained virtually unchanged since they were first established in the beginning of the XX century. One major contributing factor to this slow progress is the limited ...

Hydrological and environmental variables outperform spatial factors in structuring species, trait composition, and beta diversity of pelagic algae

Abstract There has been increasing interest in algae-based bioassessment, particularly, trait-based approaches are increasingly suggested. However, the main drivers, especially the contribution of hydrological variables, of species composition, trait compo ...

New therapeutic strategies to treat human cancers expressing mutant p53 proteins

The tumor suppressor p53 plays a critical role to preserve DNA fidelity from diverse insults through the regulation of cell-cycle checkpoints, DNA repair, senescence and apoptosis. The TP53 is the most frequently... ...

Clinical prevalence of Lewy body dementia

The prevalence of dementia with Lewy bodies (DLB) and dementia in Parkinson’s disease (PDD) in routine clinical practice is unclear. Prevalence rates observed in clinical and population-based cohorts and neuro... ...

The knowledge, attitudes and practices of doctors regarding antibiotic resistance at a tertiary care institution in the Caribbean

Antibiotic resistance (ABR) is a serious threat that requires coordinated global intervention to prevent its spread. There is limited data from the English-speaking Caribbean. ...

Applied Sciences, Vol. 8, Pages 291: Competitive Time Marching Solution Methods for Systems with Friction-Induced Nonlinearities

Applied Sciences, Vol. 8, Pages 291: Competitive Time Marching Solution Methods for Systems with Friction-Induced Nonlinearities Applied Sciences doi: 10.3390/app8020291 Authors: Chiara Gastaldi Teresa Berruti ...

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