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Health Well

It's Time to Dump Most Central Banks

Steve H. Hanke On March 16th, the  New York Times  carried reportage by Peter S. Goodman, Keith Bradsher and Neil Gough, which was titled “The Fed Acts. Workers in Mexico and Merchants in Malaysia Suffer.” The theme of their extensive reportage is that U. ...

The BMJ Awards 2017: Cancer Care

New cancer drugs for childrenOverall survival among children with cancer is good, but progress has been slower in those with high risk malignancies and with relapsed or refractory disease. ...

The BMJ Awards 2017: Cancer Care

New cancer drugs for childrenOverall survival among children with cancer is good, but progress has been slower in those with high risk malignancies and with relapsed or refractory disease. ...

Envisioning future scholarly communication: The Vienna Principles

In June 2016, we published the Vienna Principles: A Vision for Scholarly Communication in the 21st Century. The set of twelve principles describes the visions and foundations of a scholarly communication system that is based on the notion of openness in s ...

A “specialist first” system would increase waiting times

Greenfield and colleagues argue that gatekeeping is associated with delayed diagnosis and adverse outcomes for patients.1 But they do not present a strong enough argument that a “specialist first”... ...

A “specialist first” system would increase waiting times

Greenfield and colleagues argue that gatekeeping is associated with delayed diagnosis and adverse outcomes for patients.1 But they do not present a strong enough argument that a “specialist first”... ...

Trump's Wars

Emma Ashford ...

Separate Art and State

Michael D. Tanner As the husband and stepfather of accomplished artists, I take art very seriously. It is, in the words of President Kennedy, “close to the center of a nation’s purpose and a test of the quality of a nation’s civilization.” But for all tha ...

Day 2: Tendentious Progsplaining of Originalism Proves Unsuccessful Tactic for Derailing Neil Gorsuch

Ilya Shapiro ...

Synthesis and Detonation Properties of 5-Amino-2,4,6-trinitro-1,3-dihydroxy-benzene

Abstract 5-Amino-4,6-dinitro-1,3-dihydroxy-benzene (6) was synthesized through the ring-opening reaction of macrocyclic compound  4 with the aid of VNS (vicarious nucleophilic substitution of hydrogen) reaction conditions. The mechanism of ring opening of ...

A long gaze back on medicine

Dr Muiris Houston Following her reading at the recent dotMD 2017 meeting, author and broadcaster Sinéad Gleeson was interviewed by Dr Muiris Houston about her work, and life-long interactions with the medical profession. Another dotMD conference navigated ...

Brexit strategy for Health

Dara Gantly Can the Irish health service secure a benefit from Brexit, asks Dara Gantly Following the granting of royal assent to the Brexit bill last week, British prime minister Theresa May is clear to notify Brussels that the UK is leaving the EU, with ...

‘My incarceration was a puzzle to me’

Dear Editor, Your ironically titled and entertaining article ‘ The Good Old Days… ’ by Dr Garrett FitzGerald (IMT, March 3, 2017) stirred up memories in this reader. I also spent a lengthy period at this sanatorium in Foynes in the 1950s as an eight-year- ...

Should we screen extensively for cancer after unprovoked venous thrombosis?

What you need to knowThe prevalence of occult cancer in patients with a first unprovoked venous thromboembolism seems to be lower (~4%) than previously reported (10%)There is limited evidence to... ...

Should we screen extensively for cancer after unprovoked venous thrombosis?

What you need to knowThe prevalence of occult cancer in patients with a first unprovoked venous thromboembolism seems to be lower (~4%) than previously reported (10%)There is limited evidence to... ...

Competition and facilitation structure plant communities under nurse tree canopies in extremely stressful environments

Abstract Nurse plant facilitation in stressful environments can produce an environment with relatively low stress under its canopy. These nurse plants may produce the conditions promoting intense competition between coexisting species under the canopy, and ...

Capture efficiency and trophic adaptations of a specialist and generalist predator: A comparison

Abstract Specialist true predators are expected to exhibit higher capture efficiencies for the capture of larger and dangerous prey than generalist predators due to their possession of specialized morphological and behavioral adaptations. We used an araneo ...

Acute ethanol exposure during late mouse neurodevelopment results in long-term deficits in memory retrieval, but not in social responsiveness

Abstract Objective Prenatal alcohol exposure can result in neurological changes in affected individuals and may result in the emergence of a broad spectrum of neurobehavioral abnormalities termed fetal alcohol spectrum disorders (FASD). The effects of etha ...

Adaptative evolution of the Vkorc1 gene in Mus musculus domesticus is influenced by the selective pressure of anticoagulant rodenticides

Abstract Anticoagulant rodenticides are commonly used to control rodent pests worldwide. They specifically inhibit the vitamin K epoxide reductase (VKORC1), which is an enzyme encoded by the Vkorc1 gene, involved in the recycling of vitamin K. Therefore, t ...

Metapopulation patterns of additive and nonadditive genetic variance in the sea bass (Dicentrarchus labrax)

Abstract Describing and explaining the geographic within-species variation in phenotypes (“phenogeography”) in the sea over a species distribution range is central to our understanding of a variety of eco-evolutionary topics. However, phenogeographic studi ...

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