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Health Well

The Efficacy of the proprioceptive neuromuscular facilitation (PNF) approach in stroke rehabilitation to improve basic activities of daily living and quality of life: a systematic review and meta-analysis protocol

Introduction Proprioceptive neuromuscular facilitation (PNF) is a widely used rehabilitation concept, although its efficacy has not yet been demonstrated in stroke survivors. The aim of this systematic review is to identify, assess and synthesise the poten ...

Protocol for the specialist supervised individualised multifactorial treatment of new clinically diagnosed type 2 diabetes in general practice (IDA): a prospective controlled multicentre open-label intervention study

Introduction We present the protocol for a multifactorial intervention study designed to test whether individualised treatment, based on pathophysiological phenotyping and individualised treatment goals, improves type 2 diabetes (T2D) outcomes. ...

Investigation of time to first presentation and extrahospital factors in the treatment of neovascular age-related macular degeneration: a retrospective cross-sectional study

Objectives To assess the time from symptom onset to treatment for neovascular age-related macular degeneration (nvAMD) and to measure the awareness of AMD in Southeast Scotland. Design Retrospective cross-sectional study. Setting Secondary care, Southeast ...

Protocol for developing a Database of Zoonotic disease Research in India (DoZooRI)

Introduction Zoonotic and emerging infectious diseases (EIDs) represent a public health threat that has been acknowledged only recently although they have been on the rise for the past several decades. On an average, every year since the Second World War, ...

New Zealand policy experts appraisal of interventions to reduce smoking in young adults: a qualitative investigation

Objectives Reducing smoking in young adults, particularly young Māori and Pacific, is vital for reducing tobacco harm and health inequalities in New Zealand (NZ). We investigated how NZ policy experts appraised the feasibility and likely effectiveness of i ...

Informing future research for carriage of multiresistant Gram-negative bacteria: problems with recruiting to an English stool sample community prevalence study

Objectives This study aims to highlight problems with recruiting to an English stool sample community prevalence study. It was part of a larger cross-sectional research to determine the risk factors for the presence of extended-spectrum beta-lactamase and ...

Adapting the emergency first aid responder course for Zambia through curriculum mapping and blueprinting

Objectives Community members are often the first to witness and respond to medical and traumatic emergencies, making them an essential first link to emergency care systems. The Emergency First Aid Responder (EFAR) programme is short course originally devel ...

Effectiveness of acupuncture for cancer pain: protocol for an umbrella review and meta-analyses of controlled trials

I ntroduction The National Comprehensive Cancer Network guidelines for adult cancer pain indicate that acupuncture and related therapies may be valuable additions to pharmacological interventions for pain management. Of the systematic reviews related to th ...

A smoking prevention photoageing intervention for secondary schools in Brazil delivered by medical students: protocol for a randomised trial

Introduction Most smokers start smoking during their early adolescence, often with the idea that smoking is glamorous; the dramatic health consequences are too far in the future to fathom. We recently designed and tested an intervention that takes advantag ...

Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students

Introduction Obesity is a global epidemic and is a risk factor for developing other comorbidities. Young adulthood is a critical period for body weight change and establishing healthy lifestyle behaviours. The ‘Freshman 15’ suggests that undergraduate stud ...

[Editorial] When a hospital becomes a prison

Imprisonment for debt has a long history. In England during the 18th and 19th centuries, for instance, thousands of people were detained in debtors' prisons for failure to pay debts. Although such institutions no longer exist, in many parts of the wor ...

[World Report] Phage therapy: revival of the bygone antimicrobial

The idea of using bacteriophages as vectors for antimicrobial therapy has existed for decades, but development towards clinical application still lags behind. Geoff Watts reports. ...

[Perspectives] Qimin Zhan: driving medical research for better health in China

“Clinical medicine + X”—the idea of integrating medicine with other disciplines—is at the heart of Qimin Zhan's vision for better health in China. As President of Peking University Health Science Centre (PUHSC) and Vice Chancellor of Peking University ...

[Perspectives] Hospital histories

We never quite know what goes on behind closed doors. Hospitals are incubators for the most vital and vivid of human interactions. Much of these are secret and enclosed, sealed against the outside world. We are stripped down, as patients, wheeled on a trol ...

[Correspondence] Health-care delivery for long-term survivors of childhood cancer

In their Article in The Lancet (Dec 9, p 2569),1 Bhakta and colleagues provide compelling data and novel statistical analysis to quantify the overwhelming lifetime cumulative burden of chronic health conditions caused by curative paediatric cancer therapie ...

[Correspondence] Political determinants of Sustainable Development Goals

We read with interest the article by the GBD 2016 SDG Collaborators1 (Sept 16, p 1423), which presents a comprehensive analysis of the potential gaps and gains in the health-related Sustainable Development Goals by 2030. ...

[Correspondence] Anonymity in HIV testing: implications for public health

To end the HIV epidemic, UNAIDS has set an ambitious target: by 2020, 90% of the people living with HIV will be diagnosed, 90% of those diagnosed will receive antiretroviral therapy (ART), and 90% of those receiving ART will be virally suppressed.1 The tes ...

[Correspondence] Overestimation of cardiovascular outcome incidence

We read with interest the study by Michael Böhm and colleagues (June 3, p 2226),1 in which they investigated the associations between blood pressure and cardiovascular outcomes and suggested that the lowest blood pressure possible is not the best goal for ...

[Correspondence] Overestimation of cardiovascular outcome incidence – Authors' reply

We thank Yuanzi Ye and Ricardo Fonseca for their interest in our Article.1 We agree that the cumulative incidence of each outcome is slightly overestimated when the simple technique for calculating Kaplan-Meier curves is used instead of a more sophisticate ...

[Correspondence] Antiplatelet cessation to manage bleeding events in elderly people

In their Article in The Lancet, Linxin Li and colleagues (June 13, p 490)1 postulated that the increased risk of bleeding events with antiplatelet therapy in patients older than 75 years is sufficient to routinely prescribe proton-pump inhibitors (PPIs) in ...

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