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Interventions to achieve long-term weight loss in obese older people: A systematic review and meta-analysis

Creator:

Oxford University Press on behalf of the British Geriatrics Society

Subject Keywords: Weight management
Topic: Chronic Conditions
Arthritis
Conditions
Musculoskeletal condition
Obesity
Chronic Conditions
Obesity
Catalogue: Systematic Reviews
Other Reviews
Type: Report
Region: United Kingdom
Description:

Purpose: the prevalence of obesity is rapidly increasing in older adults. Information is required about what interventions are effective in reducing obesity and influencing health outcomes in this age group. Design: systematic review and meta-analysis. Data sources: thirteen databases were searched, earliest date 1966 to December 2008, including Medline, CINAHL, PsycINFO, the Cochrane database and EMBASE. Study selection: we included studies with participants’ mean age 60 years and mean body mass index 30 kg/m2, with outcomes at a minimum of 1 year. Data were independently extracted by two reviewers and differences resolved by consensus. Data extraction: nine eligible trials were included. Study interventions targeted diet, physical activity and mixed approaches. Populations included patients with coronary artery disease, diabetes mellitus and osteoarthritis. Results: meta-analysis (seven studies) demonstrated a modest but significant weight loss of 3.0 kg [95% confidence interval (CI) 5.1–0.9] at 1 year. Total cholesterol (four studies) did not show a significant change: –0.36 mmol/l (95% CI –0.75 to 0.04). There was no significant change in high-density lipoprotein, low-density lipoprotein or triglycerides. In one study, recurrence of hypertension or cardiovascular events was significantly reduced (hazard ratio 0.65, 95% CI 0.50–0.85). Six-minute walk test did not significantly change in one study. Health-related quality of life significantly improved in one study but did not improve in a second study. Conclusions: although modest weight reductions were observed, there is a lack of high-quality evidence to support the efficacy of weight loss programmes in older people.  Keywords: obesity, older, weight loss, meta-analysis, elderly, systematic review

Date:

26/01/2010

DOI:

10.14655/415-9809

Rights: Public
Suggested citation:

Oxford University Press on behalf of the British Geriatrics Society. (2010) Interventions to achieve long-term weight loss in obese older people: A systematic review and meta-analysis [Online]. Available from: http://publichealthwell.ie/node/9809 [Accessed: 17th July 2019].

  

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