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Cochrane Reviews

Pregabalin monotherapy for epilepsy

Zhou, Q., Zheng, J., Yu, L. and Jia, X. To determine the efficacy and tolerability of pregabalin in people with epilepsy A number of people continue to have seizures and many experience adverse effects, despite current antiepileptic treatments. As a resul ...

Prophylactic antibiotics to reduce the risk of urinary tract infections after urodynamic studies

Foon, R., Toozs-Hoson, P. and Latthe, P. To assess the effectiveness and safety of administering prophylactic antibiotics in reducing the risk of urinary tract infections after urodynamic studies. The hypothesis was that administering prophylactic antibio ...

Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews

Cates, C.J., et al To assess the safety of regular formoterol or salmeterol, either as monotherapy or as combination therapy, in children with asthma Asthma is a common condition that affects the airways, the small tubes that carry air in and out of the l ...

Psychosocial interventions for reducing antipsychotic medication in care home residents

Richter, T., et al To evaluate the effectiveness of psychosocial interventions to reduce antipsychotic medication in care home residents In care homes, antipsychotic medication is commonly prescribed to control so called 'behavioural and psychologica ...

Sweet-tasting solutions for needle-related procedural pain in infants one month to one year of age

Kassab, M., et al To determine the effectiveness of sweet-tasting solutions for needle-related procedural pain in infants one month to one year of age compared with no treatment, placebo, other sweet-tasting solutions, or pharmacological or other non-phar ...

Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents

Gillies, D., et al To examine the effectiveness of psychological therapies in treating children and adolescents who have been diagnosed with PTSD Post-traumatic stress disorder (PTSD) is highly prevalent in children and adolescents who have experienced tr ...

Recombinant human growth hormone for treating burns and donor sites

Breedervel, R. and Tuinebreijer, W.E. To determine the effects of rhGH on the healing rate of burn wounds and donor sites in people with burns. Growth hormone is produced by the pituitary gland. For decades, it could only be obtained by extraction from pi ...

ultimedia educational interventions for consumers about prescribed and over-the-counter medications

Ciciriello, S., et al To assess the effects of multimedia patient education interventions about prescribed and over-the-counter medications in people of all ages, including children and carers Consumers need detailed information about their medications to ...

Oral evening primrose oil and borage oil for eczema

Bamford, J.T.M., et al To assess the effects of oral evening primrose oil or borage oil for treating the symptoms of atopic eczema Eczema is an itchy and red skin condition, which may affect 20% of people world wide at some time in their life. Though it m ...

Parent-mediated early intervention for young children with autism spectrum disorders (ASD)

Oono, I.P., et al To assess the effectiveness of parent-mediated early interventions in terms of the benefits for both children with ASD and their parents and to explore some potential moderators of treatment effect Autism spectrum disorders (ASD) affect ...

Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities

Rana, F., Gormez, A. and Varghese, S. To determine clinical effectiveness of pharmacological interventions in management of self-injurious behaviour in adults with intellectual disability Self-injurious behaviour (SIB) among people with intellectual disab ...

Phyllanthus species versus antiviral drugs for chronic hepatitis B virus infection

Xia, Y., et al To evaluate the benefits and harms of phyllanthus species compared with antiviral drugs for patients with chronic HBV infection. Chronic hepatitis B virus (HBV) infection causes significant mortality, morbidity, and it is an economic burden ...

Physical exercise training interventions for children and young adults during and after treatment for childhood cancer

Braam, K.I., et al To evaluate the effect of a physical exercise training intervention (at home, at a physical therapy centre, or hospital based) on the physical fitness of children with cancer, in comparison with the physical fitness in a care as usual c ...

Physical tests for shoulder impingements and local lesions of bursa, tendon or labrum that may accompany impingement

Hanchard, N.C.A., et al To evaluate the diagnostic accuracy of physical tests for shoulder impingements (subacromial or internal) or local lesions of bursa, rotator cuff or labrum that may accompany impingement, in people whose symptoms and/or history sug ...

Rutosides for prevention of post-thrombotic syndrome

Morling, J.R., et al To determine the effectiveness and safety of rutosides for prevention of PTS in patients with DVT, compared to placebo, no intervention, or reference medication Blood clots in the veins of the leg are a common problem and are termed d ...

Rutosides for treatment of post-thrombotic syndrome

Morling, J.R., et al To determine the effectiveness and safety of rutosides for treatment of PTS in patients with DVT compared to placebo, no intervention, elastic compression stockings (ECS) or any other treatment Blood clots in the veins of the leg are ...

Screening women for intimate partner violence in healthcare settings

Taft, A., et al To assess the effectiveness of screening for intimate partner violence conducted within healthcare settings for identification, referral to support agencies and health outcomes for women Women who have experienced physical, psychological o ...

Sulphonylurea monotherapy for patients with type 2 diabetes mellitus

Hemmingsen, B., et al To assess the effects of sulphonylurea monotherapy versus placebo, no intervention or other antidiabetic interventions for patients with T2DM Sulphonylureas are widely used for patients with type 2 diabetes mellitus. Sulphonylureas l ...

Swimming training for asthma in children and adolescents aged 18 years and under

Beggs, S., et al To determine the effectiveness and safety of swimming training as an intervention for asthma in children and adolescents aged 18 years and under Asthma is a common condition among children and adolescents causing intermittent wheezing, co ...

The medical use of cannabis for reducing morbidity and mortality in patients with HIV/AIDS

Lutge, E., et al To assess whether cannabis (in its natural or artificially produced form), either smoked or ingested, decreases the morbidity or mortality of patients infected with HIV The use of cannabis (marijuana), its active ingredient or synthetic f ...