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Systematic reviews

Deep Impact: Unintended consequences of journal rank

Brembs, B. and Munafo, < Open Access publishing Most researchers acknowledge an intrinsic hierarchy in the scholarly journals (‘journal rank’) that they submit their work to, and adjust not only their submission but also their reading strategies accord ...

Exploring the Effects of a Transition to Open Access: Insights from a Simulation Study

Bernius, S., et al Open Access publishing The Open Access (OA) movement, which postulates gratis and unrestricted online access to publicly funded research findings, has significantly gained momentum in recent years. The two ways of achieving OA are self- ...

Wound drainage after plastic and reconstructive surgery of the breast

Stojkovic, C.A., et al To compare the safety and efficacy of the use of wound drains following elective plastic and reconstructive surgery procedures of the breast Plastic and reconstructive surgery of the breast can include breast enlargement, breast red ...

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia

Declercq, T., et al To evaluate whether withdrawal of antipsychotic agents is successful in older people with dementia in community or nursing home settings, to list the different strategies for withdrawal of antipsychotic agents in older people with deme ...

Vasopressin and its analogues for the treatment of refractory hypotension in neonates

shivanna, B., et al The rimary objective was to evaluate the efficacy and safety of vasopressin and its synthetic analogues (e.g. terlipressin) in decreasing mortality and adverse neurodevelopmental outcomes, and improving survival in neonates with refrac ...

Thromboprophylaxis for trauma patients

Barrera, L.M., et al To assess the effects of thromboprophylaxis in trauma patients on mortality and incidence of deep vein thrombosis and pulmonary embolism. To compare the effects of different thromboprophylaxis interventions and their effects according ...

The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission

Muchtar, E., et al To examine the efficacy and safety of maintenance therapy in APL patients and to establish the optimal regimen for maintenance Acute promyelocytic leukemia (APL) is a subtype of acute myelogenous leukemia (AML), comprising about 10% of ...

Sulthiame add-on therapy for epilepsy

Milburn-McNulty, P., et al To compare the efficacy and side-effect profile of sulthiame as add-on therapy compared with placebo or another antiepileptic drug Epilepsy is a common neurological condition which is characterised by recurrent seizures. The maj ...

Subintimal angioplasty for chronic lower limb arterial occlusion

Zhi Hui Chang and Zhao Yu Liu To assess the effectiveness of SIA versus any other treatment for patients with chronic lower limb artery occlusion. This will be determined by the effects on clinical improvement, technical success rate, patency rate, limb s ...

Stent graft types for endovascular repair of thoracic aortic aneurysms

Rolph, R., et al This review aimed to assess the different stent graft types for endovascular repair of thoracic aortic aneurysms An aneurysm is a localised widening of an artery. The thoracic aorta is the largest artery in the body, delivering blood from ...

Stent graft types for endovascular repair of abdominal aortic aneurysms

Duffy, J.M.N., et al This review aimed to assess the different stent graft types for endovascular repair of AAA An aneurysm is a localised widening of an artery. The abdominal aorta is the largest artery in the body, delivering blood from the heart to the ...

Single dose oral ibuprofen plus codeine for acute postoperative pain in adults

Derry, S., Karlin, S.M. and Moore, R.A. To assess the analgesic efficacy and adverse effects of a single oral dose of ibuprofen plus codeine for moderate to severe postoperative pain. We compared ibuprofen plus codeine with placebo and with the same dose ...

Pathogen-reduced platelets for the prevention of bleeding

Butler, C., et al To assess the effectiveness of pathogen-reduced platelets for the prevention of bleeding in patients requiring platelet transfusions Blood for transfusion is collected from donors and then processed and stored as bags of different blood ...

Oxcarbazepine for neuropathic pain

Zhou, M., et al To determine the benefits and harms of oxcarbazepine for different forms of neuropathic pain Neuropathic pain is pain that arises from damage to the part of the nervous system that carries sensory information to the brain. It is difficult ...

Osmotic therapies added to antibiotics for acute bacterial meningitis

Wall, E.C.B., et al To evaluate the effects on mortality, deafness and neurological disability of osmotic therapies added to antibiotics for acute bacterial meningitis in children and adults Meningitis is a condition where bacteria, fungi or viruses sprea ...

Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack

MacKay-Lyons, M., et al Non-pharmacological interventions, Secondary vascular events, Vascular risk factors, Stroke, Transient ischemic attack (TIA) Stroke is the second leading cause of adult death worldwide. There is increasing evidence that individuals ...

Nidotherapy for people with schizophrenia

Chamberlain, i.J. and Sampson, S. Nidotherapy, Standard care, No treatment, Schizophrenia, Disorders Nidotherapy (from the Latin ‘ nidus ’ or ‘nest’) aims at identifying the need for and making changes to a person’s environment and surroundings. It works ...

Multidimensional rehabilitation programmes for adult cancer survivors

Scott, D.A., et al MDRPs, Physical well-being, Psychosocial well-being, Adult, Cancer survivors Due to improvements in detection, treatment and care an increasing number of patients are living with or surviving cancer. However, patients who survive cancer ...

Methods of term labour induction for women with a previous caesarean section

Jozwiak, M. and Dodd, J.M. Labour induction, Women, Caesarean birth, Pregnancy Worldwide, caesarean birth is common, with percentages ranging from 25% to 50% of reported births. Current clinical practice guidelines support vaginal birth and trial of labou ...

Methods for administering subcutaneous heparin during pregnancy

Sasaki, H., et al Subcutaneous heparin (UFH or LMWH), Pregnant women Pregnant women have an increased risk of venous thromboembolism (VTE) when compared with non-pregnant women because of changes in blood clotting. VTE includes deep vein thrombosis (DVT) ...