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Pentoxifylline for diabetic retinopathy

de Jesus, C.C.L. et al Diabetic retinopathy There is increasing evidence that capillary occlusion plays an important part in the development of diabetic retinopathy. Disaggregants, such as pentoxyfilline may influence the outcome and progression of diabet ...

Vitamin C and superoxide dismutase (SOD) for diabetic retinopathy

de Jesus, C.C.L. et al Effects of vitamin C and superoxide dismutase on diabetic retinopathy There is increasing evidence that diabetic retinopathy is caused by the action of free radicals. Radical scavengers like vitamin C and superoxide dismutase (SOD) ...

Debridement of diabetic foot ulcers

Edwards, J. and Stapley, S. Diabetic foot ulcers Foot ulceration is thought to affect 15% of people with diabetes at some time in their lives. Debridement is widely regarded as an effective intervention to speed up ulcer healing. The most effective method ...

Foam dressings for healing diabetic foot ulcers

Durnville, J.C., Deshpande, S., O'Meara S. and Speak, K. Diabetic foot ulcers Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many ...

Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections

Cruciani, M., Lipsky, B., Mengoli, C. and deLalla, F. Diabetic foot infections Granulocyte-colony stimulating factor (G-CSF) increases the release of neutrophil endothelial progenitor cells from the bone marrow and improves neutrophil functions, which are ...

Hydrogel dressings for healing diabetic foot ulcers

Durnville, J.C., Deshpande, S., O'Meara S. and Speak, K. Diabetic foot ulcers Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many ...

Silver based wound dressings and topical agents for treating diabetic foot ulcers

Bergin, S. and Wraight, P. Diabetic foot ulcers Foot ulceration affects 15 to 20% of people with diabetes. It is a major precursor to amputation in this patient group, and early and appropriate treatment provides the greatest opportunity for healing. The ...

Topical silver for preventing wound infection

Storm-Versloot, M.N. et al Prevention of wound infection Silver-containing treatments are popular and used in wound treatments to combat a broad spectrum of pathogens, but evidence of their effectiveness in preventing wound infection or promoting healing ...

Topical silver for treating infected wounds

Vermeulen, H. et al Treatment of chronic wounds Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their effective ...

Topical negative pressure for treating chronic wounds

Ubbink, D.T. et al Treatment of chronic wounds Chronic wounds mainly affect the elderly and those with multiple health problems. Despite the use of modern dressings, some of these wounds take a long time to heal, fail to heal, or recur, causing significan ...

Pressure relieving interventions for preventing and treating diabetic foot ulcers

Spencer, S. A. Diabetic foot ulcers Foot ulceration is thought to affect 15% of all people with diabetes at some time during their life. The objective of this review is to assess the effectiveness of pressure relieving interventions in the prevention and ...

Complex interventions for preventing diabetic foot ulceration

Dorresteijn, J.A.N., Knegsman, D.M.W. and Valk, G.D. Diabetic foot ulcers Ulceration of the feet, which can lead to the amputation of feet and legs, is a major problem for people with diabetes mellitus, and can cause substantial economic burden. Single pr ...

Patient education for preventing diabetic foot ulceration

Dorresteijn, J.A.N., Knegsman, D.M.W., Assendelft, W.J.J. and Valk, G.D. Diabetic foot ulcers Ulceration of the feet, which can result in loss of limbs and even death, is one of the major health problems for people with diabetes mellitus. The objective of ...

Preconception care for diabetic women for improving maternal and infant health

Tieu, J., Middleton, P. and Crowther, C.A. Mothers with diabetes Infants born to mothers with pre-existing type I or type II diabetes mellitus are at greater risk of congenital anomalies, perinatal mortality and significant morbidity in the short and long ...

Specialist nurses in diabetes mellitus

Loveman, E., Royle, P. and Waugh, N. Diabetes specialists The patient with diabetes has many different learning needs relating to diet, monitoring, and treatments. In many health care systems specialist nurses provide much of these needs, usually aiming t ...

Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose

Grant, S.J. et al Herbal medicines Around 308 million people worldwide are estimated to have impaired glucose tolerance (IGT); 25% to 75% of these will develop diabetes within a decade of initial diagnosis. At diagnosis, half will have tissue-related dama ...

'Human' insulin versus animal insulin in people with diabetes mellitus

Richter, B. and Neisis, G. Insulin treatment Human insulin was introduced for the routine treatment of diabetes mellitus in the early 1980s without adequate comparison of efficacy to animal insulin preparations. First reports of altered hypoglycaemia awar ...

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Siebenhofer, A. et al Insulin treatment Short acting insulin analogue use for diabetic patients is still controversial, as reflected in many scientific debates. The objective of this review is to assess the effects of short acting insulin analogues versus ...

Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus

Vardi, M. and Nini, A. Erectile dysfunction and diabetes Erectile dysfunction is a common multi-factorial complication of diabetes mellitus. Numerous strategies have been tried to overcome this diabetic complication. In recent years, phosphodiesterase typ ...

Protein restriction for diabetic renal disease

Robertson, L.M., Waugh, N. and Robertson, A. Effects of dietary protein restriction Diabetic renal disease (diabetic nephropathy) is a leading cause of end-stage renal failure. Once the process has started, it cannot be reversed by glycaemic control, but ...