menu ☰
menu ˟

Cochrane Reviews

Sulthiame add-on therapy for epilepsy

Milburn-McNulty, P., et al To compare the efficacy and side-effect profile of sulthiame as add-on therapy compared with placebo or another antiepileptic drug Epilepsy is a common neurological condition which is characterised by recurrent seizures. The maj ...

Subintimal angioplasty for chronic lower limb arterial occlusion

Zhi Hui Chang and Zhao Yu Liu To assess the effectiveness of SIA versus any other treatment for patients with chronic lower limb artery occlusion. This will be determined by the effects on clinical improvement, technical success rate, patency rate, limb s ...

Stent graft types for endovascular repair of thoracic aortic aneurysms

Rolph, R., et al This review aimed to assess the different stent graft types for endovascular repair of thoracic aortic aneurysms An aneurysm is a localised widening of an artery. The thoracic aorta is the largest artery in the body, delivering blood from ...

Stent graft types for endovascular repair of abdominal aortic aneurysms

Duffy, J.M.N., et al This review aimed to assess the different stent graft types for endovascular repair of AAA An aneurysm is a localised widening of an artery. The abdominal aorta is the largest artery in the body, delivering blood from the heart to the ...

Single dose oral ibuprofen plus codeine for acute postoperative pain in adults

Derry, S., Karlin, S.M. and Moore, R.A. To assess the analgesic efficacy and adverse effects of a single oral dose of ibuprofen plus codeine for moderate to severe postoperative pain. We compared ibuprofen plus codeine with placebo and with the same dose ...

Pathogen-reduced platelets for the prevention of bleeding

Butler, C., et al To assess the effectiveness of pathogen-reduced platelets for the prevention of bleeding in patients requiring platelet transfusions Blood for transfusion is collected from donors and then processed and stored as bags of different blood ...

Oxcarbazepine for neuropathic pain

Zhou, M., et al To determine the benefits and harms of oxcarbazepine for different forms of neuropathic pain Neuropathic pain is pain that arises from damage to the part of the nervous system that carries sensory information to the brain. It is difficult ...

Osmotic therapies added to antibiotics for acute bacterial meningitis

Wall, E.C.B., et al To evaluate the effects on mortality, deafness and neurological disability of osmotic therapies added to antibiotics for acute bacterial meningitis in children and adults Meningitis is a condition where bacteria, fungi or viruses sprea ...

Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack

MacKay-Lyons, M., et al Non-pharmacological interventions, Secondary vascular events, Vascular risk factors, Stroke, Transient ischemic attack (TIA) Stroke is the second leading cause of adult death worldwide. There is increasing evidence that individuals ...

Nidotherapy for people with schizophrenia

Chamberlain, i.J. and Sampson, S. Nidotherapy, Standard care, No treatment, Schizophrenia, Disorders Nidotherapy (from the Latin ‘ nidus ’ or ‘nest’) aims at identifying the need for and making changes to a person’s environment and surroundings. It works ...

Multidimensional rehabilitation programmes for adult cancer survivors

Scott, D.A., et al MDRPs, Physical well-being, Psychosocial well-being, Adult, Cancer survivors Due to improvements in detection, treatment and care an increasing number of patients are living with or surviving cancer. However, patients who survive cancer ...

Methods of term labour induction for women with a previous caesarean section

Jozwiak, M. and Dodd, J.M. Labour induction, Women, Caesarean birth, Pregnancy Worldwide, caesarean birth is common, with percentages ranging from 25% to 50% of reported births. Current clinical practice guidelines support vaginal birth and trial of labou ...

Methods for administering subcutaneous heparin during pregnancy

Sasaki, H., et al Subcutaneous heparin (UFH or LMWH), Pregnant women Pregnant women have an increased risk of venous thromboembolism (VTE) when compared with non-pregnant women because of changes in blood clotting. VTE includes deep vein thrombosis (DVT) ...

Interventions to improve professional adherence to guidelines for prevention of device-related infections

Flodgren, G., et al Healthcare professional, Healthcare organisation, Infection control guidelines, Device-related infection rates Healthcare-associated infections (HAIs) are a major threat to patient safety, and are associated with mortality rates varyin ...

Inhaled corticosteroids for subacute and chronic cough in adults

Johnstone, K., et al Chronic cough, Adults Persistent cough is a common clinical problem. Despite thorough investigation and empirical management, a considerable proportion of those people with subacute and chronic cough have unexplained cough, for which ...

Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions

Arbyn, M., et al Women, ASCUS, LSIL, Cytological test, High-risk type, Human papillomavirus (hrHPV), Cervical cancer Atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intra-epithelial lesions (LSIL) are minor lesions of t ...

Helicopter emergency medical services for adults with major trauma

GalvagroJr., S.M., et l Helicopter emergency medical services transport (HEMS), Morbidity, Mortality, Ground emergency medical services transport (GEMS), Adults, Major trauma,Survival, Hospital discharge Trauma is a leading cause of death and disability w ...

FSH replaced by low-dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques

Martins, W.P., et al Low-dose hCG, FSH, Late follicular phase, Women, Assisted reproduction, Pregnancy, Ovary Follicle-stimulating hormone (FSH)- a relatively expensive drug- is commonly used for several days to stimulate the ovaries of women undergoing a ...

Folic acid supplementation during pregnancy for maternal health and pregnancy outcomes

Lassi, Z.S., et al Oral folic acid supplementation, Micronutrient, Pregnancy, Haematological, Biochemical parameters, Pregnancy outcomes Folate is a naturally occurring vitamin while folic aid is the synthetic replacement of folate used in most supplement ...

Effectiveness of the Valsalva Manoeuvre for reversion of supraventricular tachycardia

Smith, G.D., et al Valsalva Manoeuvre, Supraventricular tachycardia Supraventricular tachycardia (SVT) is a common heart abnormality which presents as a fast heart rate. This heart rhythm disturbance can occur in healthy individuals and may include sympto ...