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Systematic reviews

Pressure relieving interventions for preventing and treating diabetic foot ulcers

Spencer, S. A. Diabetic foot ulcers Foot ulceration is thought to affect 15% of all people with diabetes at some time during their life. The objective of this review is to assess the effectiveness of pressure relieving interventions in the prevention and ...

Complex interventions for preventing diabetic foot ulceration

Dorresteijn, J.A.N., Knegsman, D.M.W. and Valk, G.D. Diabetic foot ulcers Ulceration of the feet, which can lead to the amputation of feet and legs, is a major problem for people with diabetes mellitus, and can cause substantial economic burden. Single pr ...

Patient education for preventing diabetic foot ulceration

Dorresteijn, J.A.N., Knegsman, D.M.W., Assendelft, W.J.J. and Valk, G.D. Diabetic foot ulcers Ulceration of the feet, which can result in loss of limbs and even death, is one of the major health problems for people with diabetes mellitus. The objective of ...

Preconception care for diabetic women for improving maternal and infant health

Tieu, J., Middleton, P. and Crowther, C.A. Mothers with diabetes Infants born to mothers with pre-existing type I or type II diabetes mellitus are at greater risk of congenital anomalies, perinatal mortality and significant morbidity in the short and long ...

Specialist nurses in diabetes mellitus

Loveman, E., Royle, P. and Waugh, N. Diabetes specialists The patient with diabetes has many different learning needs relating to diet, monitoring, and treatments. In many health care systems specialist nurses provide much of these needs, usually aiming t ...

Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose

Grant, S.J. et al Herbal medicines Around 308 million people worldwide are estimated to have impaired glucose tolerance (IGT); 25% to 75% of these will develop diabetes within a decade of initial diagnosis. At diagnosis, half will have tissue-related dama ...

'Human' insulin versus animal insulin in people with diabetes mellitus

Richter, B. and Neisis, G. Insulin treatment Human insulin was introduced for the routine treatment of diabetes mellitus in the early 1980s without adequate comparison of efficacy to animal insulin preparations. First reports of altered hypoglycaemia awar ...

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Siebenhofer, A. et al Insulin treatment Short acting insulin analogue use for diabetic patients is still controversial, as reflected in many scientific debates. The objective of this review is to assess the effects of short acting insulin analogues versus ...

Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus

Vardi, M. and Nini, A. Erectile dysfunction and diabetes Erectile dysfunction is a common multi-factorial complication of diabetes mellitus. Numerous strategies have been tried to overcome this diabetic complication. In recent years, phosphodiesterase typ ...

Protein restriction for diabetic renal disease

Robertson, L.M., Waugh, N. and Robertson, A. Effects of dietary protein restriction Diabetic renal disease (diabetic nephropathy) is a leading cause of end-stage renal failure. Once the process has started, it cannot be reversed by glycaemic control, but ...

Interventions for latent autoimmune diabetes (LADA) in adults

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Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus

Masso, M.L. et al Type 1 diabetes Type 1 diabetes is a metabolic disorder resulting from a defect in insulin secretion. Onset of type 1 diabetes mellitus may occur at any age and it is one of the most common chronic diseases of childhood and adolescence. ...

Routine hospital admission versus out-patient or home care in children at diagnosis of type 1 diabetes mellitus

Clar, C. Waugh, N. and Thomas, S. Treatment of children newly diagnosed with type 1 diabetes In many places, children newly diagnosed with type 1 diabetes mellitus are admitted to hospital for metabolic stabilisation and training, even if they are not acu ...

Acamprosate for alcohol dependence

Rosner, S. et al Alcohol dependency Alcohol dependence is among the main leading health risk factors in most developed and developing countries. Therapeutic success of psychosocial programs for relapse prevention is moderate, but could potentially be incr ...

Baclofen for alcohol withdrawal

Liu, J. and Wang, L. Alcohol dependency The treatment of baclofen can rapidly reduce symptoms of severe alcohol withdrawal syndrome (AWS) in alcoholic patients, with a significant reduction in the cost. Baclofen is easily manageable, what's more, no ...

Benzodiazepines for alcohol withdrawal

Arnato, L., Minozzi, S., Vecchi, S. and Davoli, M. Alcohol dependency Alcohol abuse and dependence represents a serious health problem worldwide with social, interpersonal and legal interpolations. Benzodiazepines have been widely used for the treatment o ...

Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses

Leone, M.A. et al Alcohol dependency Chronic excessive alcohol consumption may lead to dependence, and to alcohol withdrawal syndrome (AWS) in case of abrupt drinking cessation. Gamma-hydroxybutyric acid (GHB) can prevent and suppress withdrawal symptoms, ...

Opioid antagonists for alcohol dependence

Rosner, S. et al Alcohol dependency Alcohol dependence belongs to the globally leading health risk factors. Therapeutic success of psychosocial programs for relapse prevention is moderate and could be increased by an adjuvant treatment with the opioid ant ...

Pharmacologic Interventions for Pregnant Women Enrolled in Alcohol Treatment

Smith, E.J., Lui, S. and Terplan, M. Interventions in pregnant women enrolled in alcohol treatment Excessive alcohol use during pregnancy has been associated with adverse maternal and neonatal effects. It is therefore important to develop and evaluate eff ...

Psychotropic analgesic nitrous oxide for alcoholic withdrawal states

Gillman, M.A., Lichtgfeld, F. and Young, T. Alcohol dependency Alcoholism is a global problem with 5-10% of the world's population demonstrating alcohol-related diseases. One of the most severe consequences of alcohol dependence is the withdrawal syn ...