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Systematic reviews

Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

Bjelakovic, G., et al Antioxidant supplements, Mortality, Adults Previous research on animal and physiological models suggests that antioxidant supplements have beneficial effects that may prolong life. Some observational studies also suggest that antioxi ...

Glucosamine therapy for treating osteoarthritis

Towheed, T., et al Randomized controlled trials (RCTs), Toxicity, Glucosamine in Osteoarthritis What is osteoarthritis and glucosamine?   Osteoarthritis (OA) is the most common form of arthritis that can affect the hands, hips, shoulders and knees. In OA, ...

Interprofessional collaboration: effects of practice-based interventions on professional practice and healthcare outcomes

Zwarenstein, M., et al Interprofessional collaboration (IPC), Interventions The extent to which different healthcare professionals work well together can affect the quality of the health care that they provide. If there are problems in how healthcare prof ...

Fluoride varnishes for preventing dental caries in children and adolescents

Marinho, V.C.C., et al Fluoride varnishes, Dental caries, Children, Adolescents Tooth decay (dental caries) is a significant health problem worldwide. It affects not only the vast majority of adults but also children, from 60% to 90% of them. In other wor ...

Antioxidants for female subfertility

Showell, M.G., et al Supplementary oral antioxidant, Placebo, Treatment, Standard treatment, Fertility outcomes, Subfertile women Review question: Do supplementary oral antioxidants compared with placebo, no treatment/standard treatment or another antioxi ...

Nebulised hypertonic saline solution for acute bronchiolitis in infants

Zhang, L., et al Nebulised hypertonic, Saline solution, Infant, Acute viral bronchiolitis Acute viral bronchiolitis is the most common lower respiratory tract infection in infants up to two years old. Currently there is no effective treatment so standard ...

Hydroxyzine for generalised anxiety disorder

Guaiana, G., et al Hydroxyzine, Placebo, Active agent, Alleviation, Acute symptoms of GAD Hydroxyzine is an anti-histamine medication that has been studied in anxiety disorders. This review shows that hydroxyzine is better than placebo in terms of anxiety ...

The heights and weights of Irish children from the post-war era to the Celtic tiger

Perry, Ivan J.; Whelton, Helen; Harrington, Janas; Cousins, Bernard; Childhood obesity; Historical trends; Height; Weight; Obesity in children-- Ireland; Social change-- Ireland-- 20th century; Health surveys-- Ireland; Accepted Version Obesity Systematic ...

Pre-Graduation Transition Services for Persons with Autism Spectrum Disorders: Effects on Employment Outcomes

westbrook, JD., et al To determine the effectiveness of pre-graduation interventions aimed at persons with autism spectrum disorders to shape behaviors, social interactions, and/or skills that result in employment in mainstream competitive employment sett ...

Systemic treatments for the prevention of venous thrombo-embolic events in paediatric cancer patients with tunnelled central venous catheters

Schoot, RA., et al To investigate the effects of preventive systemic treatments in paediatric cancer patients with tunnelled CVCs on (a)symptomatic VTE Children with cancer are at higher risk of thrombosis than children without cancer. This is a result of ...

Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese patients

Nicholson, A., et al To examine whether supraglottic airway devices can be used as a safe and effective alternative to tracheal intubation in securing the airway during general anaesthesia in obese patients (with a body mass index (BMI) > 30 kg/m2) Pat ...

Supported employment for adults with severe mental illness

Kinoshita, Y., et al To review the effectiveness of supported employment compared with other approaches to vocational rehabilitation or treatment as usual People with mental health problems experience high rates of unemployment. There are various schemes ...

Search strategies to identify diagnostic accuracy studies in MEDLINE and EMBASE

Beynon, R., et al To systematically review empirical studies that report the development or evaluation, or both, of methodological search filters designed to retrieve DTA studies in MEDLINE and EMBASE A diagnostic test is any kind of medical test performe ...

Perioperative nutrition interventions for women with ovarian cancer

Billson, HA., et al This review was conducted to assess the effects of nutrition interventions during the perioperative period for women with ovarian cancer Women who have ovarian cancer, (a cancer which develops in the two organs (ovaries) that produce e ...

Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults

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Interventions for managing relapse of the lower front teeth after orthodontic treatment

Yu, Y., et al Orthodontic treatment, Teeth, Oral Health Review question The main question addressed by this review is how effective are fixed braces or removable retainers for managing relapse of lower front teeth after orthodontic treatment, compared to ...

Interventions for helping people adhere to compression treatments for venous leg ulceration

Weller, C., et al Venous leg ulcer, Compression therapy Venous leg ulcers take weeks- or months- to heal, cause distress, and are very costly for health services. Although compression, using bandages or stockings, helps healing and prevents recurrence, ma ...

Early versus delayed dressing removal after primary closure of clean and clean-contaminated surgical wounds

Toon, CD., et al Dressing, Surgical incision site, Early dressing removal, Infection Most surgical procedures involve a cut in the skin that allows the surgeon to gain access to the deeper tissues or organs. Most surgical wounds are closed fully at the en ...

Cognitive behavioural therapies for fibromyalgia

Bernardy, K., et al Cognitive behavioural therapies (CBTs), Fibromyalgia (FM) Researchers in The Cochrane Collaboration conducted a review of research about the effects of cognitive-behavioural therapies (CBTs) on fibromyalgia (FM). After searching for al ...

Chinese herbal medicine for atopic eczema

gu, S., et al Oral ingestion, Topical application, CHM, Eczema, Children, Adult Atopic eczema (eczema in short) is a common skin condition, where skin changes occur and cause redness, scaling, swelling, and skin thickening due to chronic scratching. It is ...