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Systematic reviews

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within community dwelling populations

Quinn, T.J., et al Questionnaire, IQCODE, Detection, Dementia, Community-dwelling. Adults, Cognitive assessment Various tools exist for initial assessment of possible dementia with no consensus on the optimal assessment method. Instruments that use collat ...

Indwelling bladder catheterisation as part of intraoperative and postoperative care for caesarean section

Abdel-Aleem, H., et al Indwelling bladder catheterisation, Intraoperative, Postoperative care, Women, Caesaren section (CS) Caesaren section (CS) has become the most common obstetric surgery, with one in three of pregnant women having a caesarean delivery ...

Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B

Athale, A.H., et al Immune tolerance induction, Inhibitors, Congenital haemophilia A or B Haemophilia A and B are inherited bleeding disorders, where affected people are missing a clotting factor in their blood, which is needed for normal blood clotting. ...

Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials

Anglemyer, A., et al Observational study design Researchers and organizations often use evidence from randomized controlled trials (RCTs) to determine the efficacy of a treatment or intervention under ideal conditions, while studies of observational desig ...

Gabapentin for chronic neuropathic pain and fibromyalgia in adults

Moore, R.A., et al Gabapentin, Chronic neuropathic pain, Fibromyalgia Neuropathic pain is pain coming from damaged nerves. It differs from pain messages carried along healthy nerves from damaged tissue (a fall, cut, or arthritic knee). Neuropathic pain is ...

Fixed-dose combination therapy for the prevention of cardiovascular disease

de Cates, A.N., et al Fixed-dose combination therapy, Fatal CVD, Non-fatal CVD, Bloodpressure, Lipid CVD, Risk factor, Prevention Cardiovascular diseases (CVD), including heart attacks and strokes, are the leading cause of death and disability worldwide. ...

Exercise-based rehabilitation for heart failure

Taylor, R.S., et al Exercise-based rehabilitation, Mortality, Hospital admissions, Morbidity. Quality of life Background People with heart failure experience marked reductions in their exercise capacity, which has detrimental effects on their activities o ...

Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent)

Gurumurthy, M. et al Treatment modality, Granulosa cell tumours (GCTs), Ovary, Tumor Granulosa cell tumours (GCTs) of the ovary are rare ovarian tumours (2% to 5% of all ovarian cancers). Most ovarian tumours arise from the outer surface layer of the ovar ...

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression

Lihua, P. et al Intravenous sedative, Hypnotics, Anti-depression, Seizure, ECT. Depression is a common mental disorder. It can present as loss of interest or pleasure, sadness, disturbed sleep or appetite, feelings of guilt or low self worth. In 2008, the ...

Cognitive behavioural therapy (brief versus standard duration) for schizophrenia

Naeem, F. et al Schizophrenia, Mental wellbeing People with schizophrenia often hear voices or see things (hallucinations) and have strange beliefs (delusions). Characteristics of the illness are disordered thoughts, feelings, beliefs and perceptions. Peo ...

Bone marrow versus peripheral blood allogeneic haematopoietic stem cell transplantation for haematological malignancies in adults

Holtick, U., et al Bone marrow, Peripheral blood stem cell transplantation, Adult patient, Haematological malignancy Survival, Incidence of relapse, Non-relapse mortality, Disease-free survival, Transplant-related mortality, Incidence of GvHD, Engraftment ...

Anticoagulant treatment for subsegmental pulmonary embolism

Yoo, H.H.B., et al Anticoagulation therapy, Patient, Isolated subsegmental pulmonary embolism (SSPE), Incidental SSPE Acute pulmonary embolism (PE) is a common cause of death, accounting for 50,000 to 200,000 deaths annually. It is the third most common c ...

Anticoagulant treatment for subsegmental pulmonary embolism

Yoo, H.H.B., et al Anticoagulation therapy, Patient, Isolated subsegmental pulmonary embolism (SSPE), Incidental SSPE Acute pulmonary embolism (PE) is a common cause of death, accounting for 50,000 to 200,000 deaths annually. It is the third most common c ...

Alpha-blockers as medical expulsive therapy for ureteral stones

Campschroer, T., et al Medical treatment, Alpha-blocker, Pharmacotherapy, Placebo, Impact, Stone clearance rate, Ureteral stones Urinary stone disease is frequently seen in the urology practice. Symptoms include flank or abdominal pain radiating to the gr ...

Kinship Care for the Safety, Permanency, and Well-Being of Children Removed from the Home for Maltreatment: A Systematic Review

Winokur, M. Foster care placement, Safety, Well-being, Children, Removal from home, Maltreatment. Every year a large number of children around the world are removed from their homes because they are maltreated. Child welfare agencies are responsible for p ...

Educational and Skills-Based Interventions for Preventing Relationship and Dating Violence in Adolescents and Young Adults: A Systematic Review

Fellmeth, G. et al Educational skills-based intervention, Relationship, Dating, Violence, Adolescent, Young adult Educational and skills-based interventions are often used to prevent relationship and dating violence among young people. Systematic Reviews ...

Psychoanalytic/Psychodynamic Psychotherapy for Children and Adolescents Who Have Been Sexually Abused: A Systematic Review

Parker, B. and Turner, W. To assess the effectiveness of psychoanalytic/psychodynamic psychotherapy for children and adolescents who have been sexually abused. The sexual abuse of children and adolescents is a significant worldwide problem. It is associat ...

Are Metabolically Healthy Overweight and Obesity Benign Conditions?: A Systematic Review and Meta-analysis

Kramer, C.K., et al Metabolic status, Mortality, Cardiovascular event, Normal-weight, Overweight, Obese, Obesity Recent interest has focused on a unique subgroup of overweight and obese individuals who have normal metabolic features despite increased adip ...

Interventions for cutaneous Bowen's disease

Bath-Hextall, F.J., et al Therapeutic interventions, Cutaneous Bowen's disease, Skin cancer Bowen's disease is the clinical term for a particular precancerous skin lesion. These lesions rarely cause patients any symptoms, but appear as well-defi ...

Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions

Thomas, R.E., et al Randomised controlled trials (RCTs), Vaccination, Healthcare workers, Influenza, Pneumonia, Hospital admission, Respiratory illness, Older people, Resident, Long-term care institutions Older individuals in long-term care institutions ( ...