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DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition

Dietary restriction extends lifespan in diverse organisms, but the gene regulatory mechanisms and tissues mediating the increased survival are still unclear. Studies in worms and flies have revealed a number of candidate mechanisms, including the target o ...

Could martial arts fall training be safe for persons with osteoporosis?: a feasibility study

BackgroundOsteoporosis is a well-established risk factor for fall-related hip fractures. Training fall arrest strategies, such as martial arts (MA) fall techniques, might be useful to prevent hip fractures in persons with osteoporosis, provided that the t ...

Rosuvastatin for Primary Prevention in Older Persons With Elevated C-Reactive Protein...

Background: Randomized data on statins for primary prevention in older persons are limited, and the relative hazard of cardiovascular disease associated with an elevated cholesterol level weakens with advancing age. Objective: To assess the efficacy and s ...

Statins for Primary Prevention in Older Adults: Who Is High Risk, Who Is Old, and What Denotes Primary Prevention?

Whether to treat older adults with statin medications for primary prevention of cardiovascular events remains a clinical conundrum. This editorial discusses the exploratory analysis of patients 70 years or older in a trial that compared 20 mg/d of rosuvas ...

Alzheimer's Disease and Cognitive Decline

Objectives: To assess whether previous research on purported risk or protective factors for Alzheimer's disease (AD) and cognitive decline is of sufficient strength to warrant specific recommendations for behavioral, lifestyle, or pharmaceutical inte ...

Treating the Aged in Rural Communities: The Application of Cognitive-Behavioral Therapy for Depression

Many rural communities are experiencing an increase in their older adult population. Older adults who live in rural areas typically have fewer resources and poorer mental and physical health status than do their urban counterparts.Depression is the most p ...

Function-Focused Care for LTC Residents with Moderate-to-Severe Dementia: A Social Ecological Approach

Over one-third of long-term care (LTC) residents exhibit moderate-to-severe cognitive impairment. These residents are more likely to be inactive, require assistance with activities of daily living, have medical comorbidities, and be exposed to fewer oppor ...

Prevention of Overuse of Wheelchairs in Nursing Homes: US study

The number of nursing home residents in the United States is projected to reach three million by the year 2030. Currently, over 80% of residents spend time sitting in a wheelchair every day. Many of these residents are overlooked for therapeutic treatment ...

Body Mass Index and Survival in Men and Women Aged 70 to 75

From the  *Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, Perth, Western Australia;  †School of Medicine and Pharmacology,  ††School of Psychiatry and Clinical Neurosciences ...

Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort study

Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort studySummaryObjectives: To determine, using longitudinal analyses, if retirement is followed by a change in the risk of incident chronic diseases, depressive sy ...

Prevalence of Sexual Activity and Associated Factors in Men Aged 75 to 95 Years (Aus)

 Prevalence of Sexual Activity and Associated Factors in Men Aged 75 to 95 Years: A Cohort StudyBackground: Knowledge about sexuality in elderly persons is limited, and normative data are lacking.Objective: To determine the proportion of older men who are ...

How to develop and implement a national drug policy.

These updated guidelines focus on the national drug policy process, strategies and options which can be used by Member States and organizations active in the pharmaceutical sector. Each policy component is discussed, with a focus on current problems and n ...

Quantitative analysis of AIDS/HIV: development of methods to support policy making for infectious disease control.

This thesis is concerned with the development and application of methodology of quantitative analysis of the AIDS/HIV epidemic. This study aims to provide practical algorithms to analyse the surveillance data at hand, for support policy making for public ...

An evaluation of nursing interventions for smoking cessation in patients with chronic obstructive pulmonary disease.

Background: COPD is a major cause of morbidity and mortality worldwide and is predominantly caused by smoking. Smoking cessation is the primary disease modifying intervention available for this population. Following the publication of guidelines on smokin ...

DrugScope Street Drug Trends 2009: Falling Illegal Drug Quality 'Accelerates Trend' In Users Combining Different Drugs.

A downward trend in the quality of illegal drugs on the UK's street drug market could be driving changes in patterns of drug use, with users increasingly interchanging or combining a range of low quality drugs, according to DrugScope's 2009 Stre ...

Use of prescribed drugs to treat alcohol addiction.

Alcohol-dependent patients might require medically prescribed drugs to help them in the initial stages of treatment or/and to prevent relapses. The main types of drug used in the treatment of alcohol addiction are: Detoxification: â?¢ Chlordiazepoxide: Ch ...

WHO health topic: women's health.

Being a man or a woman has a significant impact on health, as a result of both biological and gender-related differences. The health of women and girls is of particular concern because, in many societies, they are disadvantaged by discrimination rooted in ...

Students drinking habits make campus unsafe.

Despite a precedence having been set over the past few years, no extraordinary measures seem to have been taken to ensure that students toed the curb at bus stops in UCD on Monday 17th â?" the first day of term. What was described as anti-social beha ...

Pathways Linking Positive Emotion and Health in Later Life

Numerous changes in physiological functioning accompany the aging process. Gradual declines in fundamental aspects of the neuroendocrine, cardiovascular, and immune systems contribute to increased risks for morbidity and mortality. Importantly, alteration ...

A Good News Story about Irish Health Care

 Life expectancy for older people in Ireland has been increasing steadily since the 1980s. Despite this, Irish life expectancies for the over 65s lagged seriously behind the EU average as recently as the mid 1990s. But Irish death rates for the over 65s d ...

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