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Macular pigment optical density in an ageing irish population: the irish longitudinal study on ageing

Nolan JM, Kenny R, O'Regan C, Cronin H, Loughman J, Connolly E, Kearney P, Loane E, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Age-related macular degeneration, Irish ~Longitudinal Study on Ageing, Macular pigme ...

Augmentation of Macular Pigment Following Supplementation with All Three Macular Carotenoids: An Exploratory Study

Connolly EE, Beatty S, Thurnham DI, Loughman J, Howard AN, Stack J, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P urpose: At the macula, the carotenoids meso-zeaxanthin (MZ), lutein (L), and zeaxanthin (Z) are collect ...

Risk Factors for Age-Related Maculopathy

Connell PP, Keane PA, O'Neill EC, Altaie RW, Loane E, Neelam K, Nolan JM, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease A ge-related maculopathy (ARM) is the leading cause of blindness in the elderly. Although bene ...

Psychophysical Function in Age-related Maculopathy

Neelam K, Nolan JM, Chakravarthy U, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease A bstract. Age-related macular degeneration (AMD), the late stage of age-related maculopathy (ARM), is the leading cause of blind registr ...

Foveal Anatomic Associations with the Secondary Peak and the Slope of the Macular Pigment Spatial Profile

Kirby M, Galea M, Loane E, Stack J, Beatty S, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. To investigate the reproducibility of the macular pig- ment (MP) spatial profile by using heterochromatic flicker pho ...

Assessment of lutein, zeaxanthin andmeso-zeaxanthin concentrations in dietary supplements by chiral high-performance liquid chromatography

Prado-Cabrero A. Beatty S. Stack J. Howard AN. Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract We investigated the concordance between actual and declared content of the three macular carot- enoids in commerciall ...

Visual Function and Its Relationship with Severity of Early, and Activity of Neovascular, Age-Related Macular Degeneration

Loughman J. Sabour-Pickett S. Nolan JM. Klien B. Klien R. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Purpose: To investigate the relationship between visual function and severity of early age-related macular degener ...

Cognitive Function and Its Relationshipwith Macular Pigment Optical Density and Serum Concentrations of its Constituent Carotenoids

Kelly D. Coen RF. Akuffo BO. Beatty S. Dennison J. Moran R. Stack J. Howard AN. Mulcahy R. Nolan JM. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease A bstract. Background: Macular pigment (MP) levels correlate with brain concentra ...

The Impact of Supplemental Macular Carotenoids in Alzheimer’s Disease:A Randomized Clinical Trial

Nolan JM. Loskutova E. Howard A. Mulcahy R. Stack J. Bolger M. Coen RF. Dennison J. Akuffo KO. Owens N.Power R. Thurnham D. Beatty S. Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract. Background: Patients with Alzheimer’s ...

SUPPLEMENTATION WITH THREE DIFFERENT MACULAR CAROTENOID FORMULATIONS IN PATIENTS WITH EARLY AGE-RELATED MACULAR DEGENERATION

Sabour-Pickett S, Beatty S, Connolly E, Loughman J, Stack J, Howard AN, Klein R, Klein BE, Meuer SM, Myers CE, Akuffo KO, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P urpose: To investigate the impact of three differ ...

Central Retinal Enrichment Supplementation Trials (CREST): Design and Methodology of the CREST Randomized Controlled Trials

Akuffo KO, Beatty S, Stack J, Dennison J, O'Regan S, Meagher KA, Peto T, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P urpose: The Central Retinal Enrichment Supplementation Trials (CREST) aim to investigate the ...

Macular Pigment, Visual Function, and Macular Disease among Subjects with Alzheimer’s Disease: An Exploratory Study

Nolan JM, Loskutova E, Howard AN, Moran R, Mulcahy R, Stack J, Bolger M, Dennison J, Akuffo KO, Owens N, Thurnham DI, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease B ackground: The macula (central retina) contains a yel ...

What is meso-zeaxanthin, and where does it come from?

Nolan JM, Meagher KA, Kashani S, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract The carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) accumulate in the central retina, where they are collectively ...

Macular Carotenoids and Age-related Maculopathy

O'Connell E, Neelam K, Nolan JM, Au Eong KG, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract Lutein (L) and zeaxanthin (Z) are concentrated at the macula, where they are collectively known as macular pigment ...

A review of the evidence germane to the putative protective role of the macular carotenoids forage-related macular degeneration

Sabour-Pickett S, Nolan JM, Loughman J, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease T here is a consensus that age-related macular degeneration (AMD) is the result of (photo)- oxidative-induced retinal injury and its ...

Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss

Kirby ML, Beatty S, Stack J, Harrison M, Greene I, McBrinn S, Carroll P, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Systematic Reviews https://www.nrci.ie/publications © Public 1 March 2013 Report Nutritional Researc ...

A Central Dip in the Macular Pigment Spatial Profile Is Associated with Age and Smoking

Kirby ML, Beatty S, Loane E, Akkali MC, Connolly EE, Stack J, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. To investigate the relationship between specific mac- ular pigment (MP) spatial profiles and risk fac ...

Apolipoprotein E Genotype Is Associated with Macular Pigment Optical Density

Loane E, McKay GJ, Nolan JM, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. Age-related macular degeneration (AMD) is the most common cause of blindness in older people in developed countries, and risk factors ...

The rationale and evidence base for a protective role of macular pigment in age-related maculopathy

Loane E, Kelliher C, Beatty S, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease ABSTRACT Age-related maculopathy (ARM) remains the most common cause of blind registration in people aged 50 years or over in the developed wo ...

Spatial Profile of Macular Pigment and Its Relationshipto Foveal Architecture

Nolan JM, Stringham J, Beatty S, Snodderly DM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. Macular pigment (MP) is composed of two dietary carotenoids, lutein and zeaxanthin, and a carotenoid generated by the retina, ...

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