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Systematic reviews

Update on Modifiable Risk Factors for Age-related Macular Degeneration

Nolan JM, O'Regan SJ, Beatty S, O'Regan GE Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Background Age-related macular degeneration (AMD) is the commonest cause of age-related blindness in developed countries, and it ...

Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss

Kirby ML, Beatty S, Stack J, Harrison M, Greene I, McBrinn S, Carroll P, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Systematic Reviews https://www.nrci.ie/publications © Public 1 March 2013 Report Nutritional Researc ...

The impact of macular pigment augmentation on visual performancein normal subjects: COMPASS

Nolan JM, Loughman J, Akkali MC, Stack J, Scanlon G, Davison P, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease T his study was conducted to investigate whether augmentation of macular pigment (MP) enhances visual perform ...

The association between macular pigment optical density and CFH, ARMS2, C2/BF, and C3 genotype

Loane E, Nolan JM, McKay GJ, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Age-related macular degeneration (AMD) is the most common cause of blindness in older people in developed countries, and risk for this condition ...

Supplementation with All Three Macular Carotenoids:Response, Stability, and Safety

Connolly E, Beatty S, Loughman J, Howard AN, Louw MS, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. This study was designed to investigate serum and macular response to, and safety of supplementation with, mes ...

A review of the evidence germane to the putative protective role of the macular carotenoids forage-related macular degeneration

Sabour-Pickett S, Nolan JM, Loughman J, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease T here is a consensus that age-related macular degeneration (AMD) is the result of (photo)- oxidative-induced retinal injury and its ...

Macular carotenoid supplementation in subjects with atypical spatial profiles ofmacular pigment

Nolan JM, Akkali MC, Loughman J, Howard AN, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease This study was designed to investigate the impact of macular carotenoid supplementation on the spatial pro fi le of macular pigme ...

Profiles of Macular Pigment Optical Density and Their Changes Following Supplemental Lutein and Zeaxannthin

Nolan JM, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease We congratulate Zeimer et al. 1 on their article, entitled ‘ Profiles of macular pigment optical density and their changes following supplemental lutein and zeaxan ...

Education Is Positively Associated with Macular Pigment:The Irish Longitudinal Study on Ageing (TILDA)

Nolan JM, Feeney J, Kenny RA, Cronin H, O'Regan C, Savva GM, Loughman J, Finucane C, Connolly E, Meagher KA, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease P URPOSE. The three carotenoids lutein, zeaxanthin, and mes ...

The Impact of Macular Pigment Augmentation on Visual Performance Using Different Carotenoid Formulations

Loughman J, Nolan JM, Howard AN, Connolly E, Meagher K, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Pu RPOSE. To investigate changes in macular pigment optical density (MPOD) and visual performance following supplemen ...

Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration

Meagher KA, Thurnham DI, Beatty S, Howard AN, Connolly E, Cummins W, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract Macular pigment (MP) is composed of lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ). The pr ...

Macular Pigment and Its Contribution to Vision

Loskutova E, Nolan JM, Howard A, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract: Three dietary carotenoids, lutein (L), zeaxanthin (Z) and meso- zeaxanthin (MZ) accumulate at the central retina (macula), where t ...

Macular Carotenoids and Age-related Maculopathy

O'Connell E, Neelam K, Nolan JM, Au Eong KG, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract Lutein (L) and zeaxanthin (Z) are concentrated at the macula, where they are collectively known as macular pigment ...

Lutein supplementation improvesvisual performance in Chinesedrivers: 1-year randomized, double-blind, placebo-controlled study: Theimportance of supplementing with allthree macular carotenoids

Nolan JM, Beatty S, Dennison J Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease To the Editor: We congratulate Yao et al [1] on their valuable contribution to the area of nutritional supplementation to maximize visual performance. ...

What is meso-zeaxanthin, and where does it come from?

Nolan JM, Meagher KA, Kashani S, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Abstract The carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) accumulate in the central retina, where they are collectively ...

Low macular pigment optical density is associated with lower cognitive performance in a large, population-based sample of older adults

Feeney J, Finucane C, Savva GM, Cronin H, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease Macular pigment (MP) is comprised of the carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ), which selectively accumu ...

Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance

Dennison JL, Stack J, Beatty S, Nolan JM Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease T his study compares in vivo measurements of macular pigment (MP) obtained using customized het- erochromatic fl icker photometry (cHFP; Macu ...

Response to Bernstein Et Al

Nolan JM, Meagher K, Kashani S, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease We welcome the letter by Bernstein et al 1 in response to our publication ‘ What is meso-zeaxanthin, and where does it come from? ’in Eye 201 ...

Macular Pigment, Visual Function, and Macular Disease among Subjects with Alzheimer’s Disease: An Exploratory Study

Nolan JM, Loskutova E, Howard AN, Moran R, Mulcahy R, Stack J, Bolger M, Dennison J, Akuffo KO, Owens N, Thurnham DI, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease B ackground: The macula (central retina) contains a yel ...

Regarding Macular Xanthophylls andω-3 Long-Chain Polyunsaturated Fatty Acids in Age-Related Macular Degeneration

Meagher KA, Nolan JM, Beatty S Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease We read with interest the recently published ar- ticle by Arnold et al titled “Macular Xanthophylls and ω-3 Long- Chain Polyunsaturated Fatty Acids in ...