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The effect of obesity combined with low muscle strength on decline in mobility in older persons

S Stenholm, D Alley, S Bandinelli, M E Griswold, S Koskinen, T Rantanen, J M Guralnik and L Ferrucci1 Research on the effect of obesity on the mobility of older people Both obesity and muscle impairment are increasingly prevalent among older persons and n ...

Vegetables and nuts come out top for heart health

A. Mente, L. de Koning, H.S. Shannon, S.S. Anand A report to show that a Mediterranean diet, rich iS associated with a lower risk for heart disease According to findings published in this week's Archives of Internal Medicine, modest relationships wer ...

Are elderly haemodialysis patients at risk of falls and postural hypotension?

The numbers of older people on haemodialysis isrising. As aging and renal failure are riskfactors for autonomic failure and haemodialysisinvolves significant fluid shifts wehypothesized that older patients would besusceptible to hypotensive events between ...

Human CD4+ T cell clone longevity in tissue culture: lack of influence of donor age or cell origin

CD4+ human T cell clones were derived from activated peripheral blood lymphocytes of healthy young adults to establish cloning efficiencies (CE) and clonal longevities. These results were compared with those obtained using cells from the very elderly, als ...

Impact of Stroke on Quality of Life of Older People

 Of the 30,000 people in Ireland with residual disability following stroke, 22% are unable to walk and between 24-53% needed help with daily living. In 2006 Murphy et al. conducted a study which explored quality of life issues for older people with a disa ...

Joint Report on Social Protection and Social inclusion, Pensions, Healthcare and Long Term care

For the first time Member States have submitted integrated National Reports on strategies for social inclusion, pensions, healthcare and long-term care.1 They have done so against the background of demographic ageing and intensified globalisation. They al ...

A randomized controlled trial of home telecare

We have established a randomized controlled trial of home telecare. The intervention aims to address a growing problem in the National Health Service (NHS), that is, high admission rates of patients with exacerbations of chronic obstructive pulmonary dise ...

Functional Foods, Ageing and Degenerative Disease (Book)

 Degenerative diseases linked to ageing populations are a growing problem for the developed world. Edited by two authorities, this important collection reviews the role of functional foods in helping to prevent a number of such degenerative conditions, fr ...

Platelet Response to Low-Dose Enteric-Coated Aspirin in Patients With Stable Cardiovascular Disease

Andrew O. Maree, MSc, MD*, Ronan J. Curtin, MSc, MD*, Michelle Dooley, BSc*, Ronan M. Conroy, BA, DSc, Peter Crean, MD, FRCPI, Dermot Cox, BSc, PhD*,* a Desmond J. Fitzgerald, MD, FRCPI* Department of Clinical Pharmacology, Royal College of Surgeons in Ir ...

Investigating the involvement of glycine receptors in the development of Parkinson's disease

Glycine is a chemical that transmits messages from one nerve cell to another. Most receptors for glycine are found at connections between nerve cells in the spinal cord and brainstem (See Figure below). These receptors also contain a pore that allows chlo ...

The Longevity Dividend- What should we be doing to prepare for the unprecedented ageing of humanity?

The Longevity Dividend- What should we be doing to prepare for the unprecedented ageing of humanity?Imagine an intervention, such as a pill, that could significantly reduce your risk of cancer. Imagine an intervention that could reduce your risk of stroke ...

Inpatient and outpatient rehabilitation for patients with rheumatoid arthritis: a clinical and economic assessment

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Measuring Health-Related Quality of Life in Older Patient Populations: A Review of Current Approaches

Hickey, Anne; Barker, Maja; McGee, Hannah; O'Boyle, CiaranThe changing demographic profile of the world's population towards old age and evidence of people living for longer with less time spent in ill health highlight the importance of addressi ...

Multifactorial intervention after a fall in older people with cognitive impairment and dementia presenting to the accident...

Fiona E Shaw, Alzheimer's Society research fellow,a John Bond, professor,b David A Richardson, clinical research associate,a Pamela Dawson, senior lecturer,c I Nicholas Steen, statistician,b Ian G McKeith, professor,d and Rose Anne Kenny, professor o ...

Towards defining the neuropathological substrates of vascular dementia

Cerebrovascular disease is highly heterogeneous but can culminate in vascular cognitive impairment or vascular dementia (VaD). As much as the clinical diagnosis warrants scrutiny, the neuropathological substrates of VaD also need to be better defined. Ath ...

Curcumin and cancer: An "old-age" disease with an "age-old" solution

Cancer is primarily a disease of old age, and that life style plays a major role in the development of most cancers is now well recognized. While plant-based formulations have been used to treat cancer for centuries, current treatments usually involve poi ...

Paying the Price- The cost of mental health care in England to 2026

Recognising the significance of mental health in terms of both expenditure and the overall health of the population, the King’s Fund commissioned a review. This report presents current and projected needs for mental health services and their related costs ...

Low HDL Cholesterol Is a Risk Factor for Deficit and Decline in Memory in Midlife. The Whitehall II Study

Objective —The purpose of this study was to examine the relationship between fasting serum lipids and short-term verbal memory in middle-aged adults.Methods and Results —Total cholesterol, high-density lipoprotein cholesterol (HDL-C), triglycerides, and m ...

What is the future for NSAIDS in preventing breast cancer in older women?

Age is the major risk factor for breast cancer in women, with 50% of cases being diagnosed in those over 65 years of age. Epidemiological evidence suggests that cyclooxygenase (COX)-2 inhibitors can reduce the incidence of breast cancer by 20% and these a ...

Role of screening in managing osteoporosis in men

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