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Primary Malignant Fibrous Histiocytoma of the Liver - 2 Cases Report -

31 Dec 1999

The malignant fibrous histiocytoma (MFH) was first introduced in 1963 to refer to a group of soft-tissue tumors characterized by a storiform or cartwheel-like growth pattern and predominantly fibroblastic appearance. It was postulated that they were derived from histiocytes that could assume the appearance and function of fibroblasts. MFH has been recognized to be the most common sarcoma in the soft tissue of late adult life which involves the deep fascia or skeletal muscles of the extremities or retroperitoneum. It has been noted in other organs, however, it rarely arises in the liver. We report two cases of primary malignant fibrous histiocytoma of the liver histopathologically confirmed after surgical resection- storiform pleomorphic and myxoid subtypes in the 55 year old male and 49 year old female patients, respectively, and describes the clinical courses, characteristics and pathologic aspects with review of the related literatures. (Korean J Hepatol 1999;5:240-245)

Click here to view the full article which appeared in Clinical and Molecular Hepatlogy