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Caution when treating tuberculosis in malnourished children

21 Aug 2018

Tuberculosis (TB) is one of the 10 leading causes of death worldwide.1 The WHO in 2016 estimated that 1 million children <15 years old suffer from TB and 250 000 died of this condition (including children with HIV-associated TB).2

Malnutrition and TB are problems of enormous magnitude in most low-income and middle-income countries, which carry the burden of 95% of cases and deaths from TB,3 and both problems are compounded in a high proportion of affected children. Nutrition is significantly poorer among patients with active TB compared with healthy controls.4 Both macronutrient and micronutrient deficiencies increase the risk of developing TB and of having poorer outcomes from TB.4 5 Malnourished patients with TB have delayed recovery and higher mortality rates than well-nourished patients; however, the nutritional status of patients with both conditions invariably improves when they receive effective TB chemotherapy.3...

Click here to view the full article which appeared in Archives of Disease in Childhood